Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Characterisation of blood-derived exosomal hTERT mRNA secretion in cancer patients: a potential pan-cancer marker

22 Jun 2017

Abstract excerpt

BACKGROUND: Telomerase (human telomerase reverse transcriptase (hTERT)) is considered a hallmark of cancer. The aim of our study was to evaluate the feasibility of the detection of hTERT transcripts in serum as a 'pan-cancer' diagnostic method. METHODS: Human telomerase reverse transcriptase mRNA levels were determined in serum and serum-derived exosomes from 133 patients with different malignancies and 45...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Extracellular vesicles in disease
Share to Single-cell and spatial transcriptomics
Share to Telomeres, Telomerase, and Senescence

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 28641311
DOI: 10.1038/bjc.2017.166

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 8 closest

Characterisation of blood-derived exosomal hTERT mRNA secretion in cancer patients: a potential pan-cancer markerPMID 28641311Read ↗

Tumor cells derived exosomes contain hTERT mRNA and transform nonmalignant fibroblasts into telomerase positive cellsSemantic proximity Read ↗

Real-Time Quantification in Plasma of Human Telomerase Reverse Transcriptase (hTERT) mRNA: A Simple Blood Test to Monitor Disease in Cancer PatientsSemantic proximity Read ↗

Exosomal Telomerase Transcripts Contribute to CAF Formation and Reprogram the MicroRNA Transcriptome Profile of the Recipient CellsSemantic proximity Read ↗

The significance of human telomerase reverse transcriptase (hTERT) in cancerSemantic proximity Read ↗

Exosomal telomerase transcripts reprogram the microRNA transcriptome profile of fibroblasts and partially contribute to CAF formationSemantic proximity Read ↗

Human telomerase reverse transcriptase messenger RNA (TERT mRNA) as a tumour marker for early detection of hepatocellular carcinomaSemantic proximity Read ↗

Circulating tumour-derived DNA and RNA markers in blood: a tool for early detection, diagnostics, and follow-up?Semantic proximity Read ↗

Exosomes as targeted diagnostic biomarkers: Recent studies and trendsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.