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Article

Bioinformatics analysis of key genes and pathways for hepatocellular carcinoma transformed from cirrhosis.

Medicine - 1 Jun 2017

He Bosheng, Yin Jianbing, Gong Shenchu, Gu Jinhua, Xiao Jing, Shi Weixiang, Ding Wenbin, He Ying

Abstract excerpt

OBJECTIVE: We aimed to identify some pivotal genes and pathways for hepatocellular carcinoma (HCC) transformation from cirrhosis and explore potential targets for treatment of the disease. METHODS: The GSE17548 microarray data were downloaded from Gene Expression Omnibus database, and 37 samples (20 cirrhosis and 17 HCC samples) were used for analysis. The differentially expressed genes (DEGs) in HCC tissues were...

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Share to Carcinoma, Hepatocellular
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Mitogen-Activated Protein Kinase Kinases

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Source

Open in PubMed Open full text

Identifiers

PMID: 28640074
DOI: 10.1097/MD.0000000000006938
PMCID: PMC5484182

Genes

CDK1
ASPM
PBK

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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