Article
Sonographic screening for Wilms tumor in children with CLOVES syndrome.
Pediatric blood & cancer - 1 Dec 2017
Peterman Caitlin M, Fevurly R Dawn, Alomari Ahmad I, Trenor Cameron C, Adams Denise M, Vadeboncoeur Sophie, Liang Marilyn G, Greene Arin K, Mulliken John B, Fishman Steven J
Abstract excerpt
BACKGROUND: CLOVES syndrome is associated with somatic mosaic PIK3CA mutations and characterized by congenital lipomatous overgrowth, vascular malformations, epidermal nevi, and skeletal anomalies. Wilms tumor (WT) is a malignant embryonal renal neoplasm associated with hemihypertrophy and certain overgrowth disorders. After identifying WT in a child with CLOVES, we questioned whether ultrasonographic screening...
Topics
- Adolescent
- Adult
- Child
- Child, Preschool
- Class I Phosphatidylinositol 3-Kinases
- Humans
- Infant
- Infant, Newborn
- Kidney Neoplasms
- Lipoma
- Middle Aged
- Musculoskeletal Abnormalities
- Mutation
- Nevus