Article
Sonographic screening for Wilms tumor in children with CLOVES syndrome.
Pediatric blood & cancer - 1 Dec 2017
Peterman Caitlin M, Fevurly R Dawn, Alomari Ahmad I, Trenor Cameron C, Adams Denise M, Vadeboncoeur Sophie, Liang Marilyn G, Greene Arin K, Mulliken John B, Fishman Steven J
Abstract excerpt
BACKGROUND: CLOVES syndrome is associated with somatic mosaic PIK3CA mutations and characterized by congenital lipomatous overgrowth, vascular malformations, epidermal nevi, and skeletal anomalies. Wilms tumor (WT) is a malignant embryonal renal neoplasm associated with hemihypertrophy and certain overgrowth disorders. After identifying WT in a child with CLOVES, we questioned whether ultrasonographic screening...
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