Efficacy of response-guided directly observed pegylated interferon and self-administered ribavirin for people who inject drugs with hepatitis C virus genotype 2/3 infection: The ACTIVATE study.

doi:10.1016/j.drugpo.2017.05.020

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Article

Efficacy of response-guided directly observed pegylated interferon and self-administered ribavirin for people who inject drugs with hepatitis C virus genotype 2/3 infection: The ACTIVATE study.

The International journal on drug policy - 1 Sept 2017

Grebely Jason, Dalgard Olav, Cunningham Evan B, Hajarizadeh Behzad, Foster Graham R, Bruggmann Philip, Conway Brian, Backmund Markus, Robaeys Geert, Swan Tracy, Amin Janaki, Marks Philippa S, Quiene Sophie, Applegate Tanya L, Weltman Martin, Shaw David, Dunlop Adrian, Hellard Margaret, Bruneau Julie, Midgard Håvard, Bourgeois Stefan, Staehelin Cornelia, Dore Gregory J

Abstract excerpt

BACKGROUND: There are few data on treatment for hepatitis C virus (HCV) infection among people with ongoing injecting drug use. This study evaluated the efficacy of response-guided therapy for chronic HCV genotypes 2/3 infection among people with ongoing injecting drug use or receiving opioid substitution therapy (OST). A secondary aim was to identify predictors of HCV treatment response. METHODS: ACTIVATE was a...

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PMID: 28624134
DOI: 10.1016/j.drugpo.2017.05.020

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