Article
Identification of 8 Novel Mutations in Nephrogenesis-Related Genes in Chinese Han Patients with Unilateral Renal Agenesis.
American journal of nephrology - 1 Jan 2017
Wu Hangdi, Xu Qian, Xie Jingyuan, Ma Jun, Qiao Panpan, Zhang Wen, Yu Haijin, Wang Weiming, Qian Ying, Zhang Qianying, Guo Yiqing, Tang Yonghua, Chen Xiao-Nong, Wang Zhaohui, Chen Nan
Abstract excerpt
BACKGROUND: Few genetic studies have focused on unilateral renal agenesis (URA), which is a disorder with insidious clinical manifestations and a tendency to result in renal failure. We aimed to detect pathogenic mutations in nephrogenesis-related genes, which were identified by a literature review conducted among a large cohort of Chinese Han patients with URA. METHODS: Totally, 86 unrelated URA patients were...
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