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Invited Commentary: The Framingham Offspring Study-A Pioneering Investigation Into Familial Aggregation of Cardiovascular Risk.

American journal of epidemiology - 1 Jun 2017

Manson JoAnn E, Bassuk Shari S

Abstract excerpt

Launched in 1948, the Framingham Heart Study was a seminal prospective cohort study of 5,209 adult residents of Framingham, Massachusetts, that was designed to uncover the determinants and natural history of coronary heart disease. Data from this original cohort established the cardiac threat posed by high blood pressure, high cholesterol, smoking, obesity, physical inactivity, diabetes, and other factors. In the...

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PMID: 28535172
DOI: 10.1093/aje/kwx068
PMCID: PMC5451291

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