Article
Phased Genotyping-by-Sequencing Enhances Analysis of Genetic Diversity and Reveals Divergent Copy Number Variants in Maize.
G3 (Bethesda, Md.) - 5 Jul 2017
Manching Heather, Sengupta Subhajit, Hopper Keith R, Polson Shawn W, Ji Yuan, Wisser Randall J
Abstract excerpt
High-throughput sequencing (HTS) of reduced representation genomic libraries has ushered in an era of genotyping-by-sequencing (GBS), where genome-wide genotype data can be obtained for nearly any species. However, there remains a need for imputation-free GBS methods for genotyping large samples taken from heterogeneous populations of heterozygous individuals. This requires that a number of issues encountered...
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