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Article

Dmrt1 induces the male pathway in a turtle with temperature-dependent sex determination

1 Jan 2017

Abstract excerpt

The molecular mechanism underlying temperature-dependent sex determination (TSD) has been a long-standing mystery; in particular, the thermo-sensitive genetic triggers for gonadal sex differentiation are largely unknown. Here, we characterized a conserved DM domain gene, Dmrt1, in the red-eared slider turtle Trachemys scripta (T. scripta), which exhibits TSD. We found that Dmrt1 has a temperature-dependent,...

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PMID: 28506988
DOI: 10.1242/dev.152033

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