Drosophila melanogaster as a High-Throughput Model for Host–Microbiota Interactions

Abstract excerpt

We agree no model is perfect and that D. melanogaster has its limitations like any other model. We would like to stress that we are not discrediting germ-free mouse models, but that researchers could benefit from supportive in vivo evidence (rather than in vitro) of their hypotheses before embarking down this expensive avenue. The cost and time-consuming nature of germ-free mouse studies requires strong...

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