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Article

Cardiosphere-Derived Cells Require Endoglin for Paracrine-Mediated Angiogenesis

1 May 2017

Abstract excerpt

Clinical trials of stem cell therapy to treat ischemic heart disease primarily use heterogeneous stem cell populations. Small benefits occur via paracrine mechanisms that include stimulating angiogenesis, and increased understanding of these mechanisms would help to improve patient outcomes. Cardiosphere-derived-cells (CDCs) are an example of these heterogeneous stem cell populations, cultured from cardiac...

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PMID: 28494939
DOI: 10.1016/j.stemcr.2017.04.015

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