Article
Can Understanding the Pathogenesis of Autoimmune Hepatitis Lead to Rational Therapy?
Digestive diseases (Basel, Switzerland) - 1 Jan 2017
Lohse Ansgar W, Herkel Johannes, Weiler-Normann Christina
Abstract excerpt
The pathogenesis of autoimmune hepatitis is still poorly understood and therefore, the therapy administered to treat this condition is broadly targeted immunosuppression. However, the aim of therapy in the future should be more specific; it should be a therapy that interrupts the pathogenetic cascade at defined checkpoints. Even though these checkpoints are not yet defined, possible targets of immunotherapy are...
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