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Article

Linalool prevents oxidative stress activated protein kinases in single UVB-exposed human skin cells

3 May 2017

Abstract excerpt

Ultraviolet-B radiation (285-320 nm) elicits a number of cellular signaling elements. We investigated the preventive effect of linalool, a natural monoterpene, against UVB-induced oxidative imbalance, activation of mitogen-activated protein kinase (MAPK) and nuclear factor kappa-B (NF-κB) signaling in HDFa cells. We observed that linalool treatment (30 μM) prevented acute UVB-irradiation (20 mJ/cm2) mediated loss...

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PMID: 28467450
DOI: 10.1371/journal.pone.0176699

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