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Article

IFT81 as a Candidate Gene for Nonsyndromic Retinal Degeneration.

Investigative ophthalmology & visual science - 1 May 2017

Dharmat Rachayata, Liu Wei, Ge Zhongqi, Sun Zixi, Yang Lizhu, Li Yumei, Wang Keqing, Thomas Kandace, Sui Ruifang, Chen Rui

Abstract excerpt

Purpose: IFT81, a core component of the IFT-B complex, involved in the bidirectional transport of ciliary proteins, has been recently implicated in syndromic ciliopathies. However, none of the IFT-B core complex proteins have been associated with nonsyndromic retinal dystrophies. Given the importance of ciliary transport in photoreceptor function and structural maintenance, we sought to investigate the impact of...

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Identifiers

PMID: 28460050
DOI: 10.1167/iovs.16-19133
PMCID: PMC5413215

Genes

IFT81

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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IFT81 as a Candidate Gene for Nonsyndromic Retinal Degeneration.PMID 28460050Read ↗

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Pharmacological rescue of cilia trafficking defects in IFT140 retinal organoid and RPE models of retinal dystrophySemantic proximity Read ↗

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A mutation in IFT43 causes non-syndromic recessive retinal degeneration.Semantic proximity Read ↗

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