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Article

Phenotypic classification of gastric signet ring cell carcinoma and its relationship with K-ras mutation.

Genetics and molecular research : GMR - 28 Apr 2017

Xiong Z F, Shi J, Fu Z H, Wan H P, Tu L X

Abstract excerpt

We aimed to analyze gastric signet ring cell (SRC) carcinoma subtypes by investigating gastric and intestinal phenotypic marker expression, and explore the relationship between phenotype and K-ras mutation. Immunohistochemistry was performed on 163 SRC carcinoma patient specimens to detect gastric (MUC1, MUC5AC, and MUC6) and intestinal (MUC2 and CDX2) phenotypic markers, and tumors were classified into gastric...

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Share to Carcinoma, Signet Ring Cell
Share to CDX2 Transcription Factor

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 28453172
DOI: 10.4238/gmr16029181

Genes

SRC
CDX2
MUC2
MUC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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