Ureaplasma Species Multiple Banded Antigen (MBA) Variation Is Associated with the Severity of Inflammation In vivo and In vitro in Human Placentae

Abstract excerpt

Background: The multiple banded antigen (MBA), a surface-exposed lipoprotein, is a major virulence factor of Ureaplasma spp. We previously demonstrated that the number of MBA size variants in amniotic fluid was inversely proportional to the severity of chorioamnionitis in pregnant sheep. However, the effect of ureaplasma MBA size variation on inflammation in human pregnancies has not been reported. Methods:...

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