Article
Transplantation of induced mesenchymal stem cells for treating chronic renal insufficiency.
PloS one - 1 Jan 2017
Pan Xing-Hua, Zhou Jing, Yao Xiang, Shu Jun, Liu Ju-Fen, Yang Jian-Yong, Pang Rong-Qing, Ruan Guang-Ping
Abstract excerpt
Discovering a new cell transplantation approach for treating chronic renal insufficiency is a goal of many nephrologists. In vitro-cultured peripheral blood mononuclear cells (PBMCs) were reprogrammed into induced mesenchymal stem cells (iMSCs) by using natural inducing agents made in our laboratory. The stem cell phenotype of the iMSCs was then identified. Unilateral ureteral obstruction (UUO) was used to create...
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