Article
MicroRNA expression profiling of Xp11 renal cell carcinoma.
Human pathology - 1 Sept 2017
Marchionni Luigi, Hayashi Masamichi, Guida Elisa, Ooki Akira, Munari Enrico, Jabboure Fayez J, Dinalankara Wikum, Raza Ali, Netto George J, Hoque Mohammad O, Argani Pedram
Abstract excerpt
Renal cell carcinomas (RCCs) with Xp11 translocation (Xp11 RCC) constitute a distinctive molecular subtype characterized by chromosomal translocations involving the Xp11.2 locus, resulting in gene fusions between the TFE3 transcription factor with a second gene (usually ASPSCR1, PRCC, NONO, or SFPQ). RCCs with Xp11 translocations comprise up to 1% to 4% of adult cases, frequently displaying papillary architecture...
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