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Dual effect of fetal bovine serum on early development depends on stage-specific reactive oxygen species demands in pigs

13 Apr 2017

Abstract excerpt

Despite the application of numerous supplements to improve in vitro culture (IVC) conditions of mammalian cells, studies regarding the effect of fetal bovine serum (FBS) on mammalian early embryogenesis, particularly in relation to redox homeostasis, are lacking. Herein, we demonstrated that early development of in vitro-produced (IVP) porcine embryos highly depends on the combination of FBS supplementation...

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PMID: 28406938
DOI: 10.1371/journal.pone.0175427

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