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A Chinese Variant Marek’s Disease Virus Strain with Divergence between Virulence and Vaccine Resistance

3 Apr 2017

Abstract excerpt

Marek's disease (MD) virus (MDV) has been evolving continuously, leading to increasing vaccination failure. Here, the MDV field strain BS/15 was isolated from a severely diseased Chinese chicken flock previously vaccinated with CVI988. To explore the causes of vaccination failure, specific-pathogen free (SPF) chickens vaccinated with CVI988 or 814 and unvaccinated controls were challenged with either BS/15 or the...

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PMID: 28368367
DOI: 10.3390/v9040071

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