Article
Scoliosis in Rett Syndrome: Progression, Comorbidities, and Predictors.
Pediatric neurology - 1 May 2017
Killian John T, Lane Jane B, Lee Hye-Seung, Skinner Steve A, Kaufmann Walter E, Glaze Daniel G, Neul Jeffrey L, Percy Alan K
Abstract excerpt
BACKGROUND: Scoliosis is prominent in Rett syndrome (RTT). Following the prior report from the US Natural History Study, the onset and progression of severe scoliosis (≥40° Cobb angle) and surgery were examined regarding functional capabilities and specific genotypes, addressing the hypothesis that abnormal muscle tone, poor oral feeding, puberty, and delays or absence of sitting balance and ambulation may be...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.