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Article

Differentially expressed miRNAs in sepsis-induced acute kidney injury target oxidative stress and mitochondrial dysfunction pathways

15 Mar 2017

Abstract excerpt

OBJECTIVE: To identify specific miRNAs involved in sepsis-induced AKI and to explore their targeting pathways. METHODS: The expression profiles of miRNAs in serum from patients with sepsis-induced AKI (n = 6), sepsis-non AKI (n = 6), and healthy volunteers (n = 3) were investigated by microarray assay and validated by quantitative PCR (qPCR). The targets of the differentially expressed miRNAs were predicted by...

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PMID: 28296904
DOI: 10.1371/journal.pone.0173292

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