Article
Effect of viral suppression on hepatic venous pressure gradient in hepatitis C with cirrhosis and portal hypertension.
Journal of viral hepatitis - 1 Oct 2017
Afdhal N, Everson G T, Calleja J L, McCaughan G W, Bosch J, Brainard D M, McHutchison J G, De-Oertel S, An D, Charlton M, Reddy K R, Asselah T, Gane E, Curry M P, Forns X
Abstract excerpt
Portal hypertension is a predictor of liver-related clinical events and mortality in patients with hepatitis C and cirrhosis. The effect of interferon-free hepatitis C treatment on portal pressure is unknown. Fifty patients with Child-Pugh-Turcotte (CPT) A and B cirrhosis and portal hypertension (hepatic venous pressure gradient [HVPG] >6 mm Hg) were randomized to receive 48 weeks of open-label sofosbuvir plus...
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