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Article

Human liver epigenetic alterations in non-alcoholic steatohepatitis are related to insulin action

23 Feb 2017

Abstract excerpt

Both genetic and lifestyle factors contribute to the risk of non-alcoholic steatohepatitis (NASH). Additionally, epigenetic modifications may also play a key role in the pathogenesis of NASH. We therefore investigated liver DNA methylation, as a marker for epigenetic alterations, in individuals with simple steatosis and NASH, and further tested if these alterations were associated with clinical phenotypes. Liver...

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PMID: 28277977
DOI: 10.1080/15592294.2017.1294305

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