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Are synchronous and metachronous bilateral breast cancers different? An immunohistochemical analysis focused on cell cycle regulation.

Histology and histopathology - 1 Jan 2018

Senkus Elżbieta, Szade Jolanta, Pieczyńska Beata, Kunc Michał, Pliszka Agnieszka, Jassem Jacek

Abstract excerpt

INTRODUCTION: The biology and pathomechanisms of bilateral breast cancers is not fully understood. We compared the morphological and immunohistochemical characteristics of primary tumors in patients with synchronous (sBBC) and metachronous bilateral breast cancers (mBBC), with special focus on cell cycle regulation and its correlation with markers determining intrinsic phenotype. METHODS: Immunohistochemical...

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PMID: 28276034
DOI: 10.14670/HH-11-887

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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