Article
HNF1B, TSPAN8 and NOTCH2 gene polymorphisms in women with gestational diabetes.
The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians - 1 Apr 2018
Tarnowski Maciej, Malinowski Damian, Safranow Krzysztof, Dziedziejko Violetta, Pawlik Andrzej
Abstract excerpt
PURPOSE: To investigate genes involved in pancreatic beta cell function, insulin production and glucose metabolism that may predispose to gestational diabetes mellitus (GDM). METHODS: The study group consisted of 204 women with GDM and 207 women with normal glucose tolerance (NGT). The following polymorphisms were genotyped for each patient: HNF1B rs4430796, TSPAN8 rs7961581 and NOTCH2 rs10923931. A p value of...
Read the complete abstract on PubMed