Article
Ancestry, Plasmodium cynomolgi prevalence and rhesus macaque admixture in cynomolgus macaques (Macaca fascicularis) bred for export in Chinese breeding farms.
Journal of medical primatology - 1 Apr 2017
Zhang Xinjun, Meng Yuhuan, Houghton Paul, Liu Mingyu, Kanthaswamy Sreetharan, Oldt Robert, Ng Jillian, Trask Jessica Satkoski, Huang Ren, Singh Balbir, Du Hongli, Smith David Glenn
Abstract excerpt
BACKGROUND: Most cynomolgus macaques (Macaca fascicularis) used in the United States as animal models are imported from Chinese breeding farms without documented ancestry. Cynomolgus macaques with varying rhesus macaque ancestry proportions may exhibit differences, such as susceptibility to malaria, that affect their suitability as a research model. METHODS: DNA of 400 cynomolgus macaques from 10 Chinese breeding...
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