Article
Synthetic analogs of rhamnolipids modulate structured biofilms formed by rhamnolipid-nonproducing mutant of Pseudomonas aeruginosa.
Bioorganic & medicinal chemistry - 15 Mar 2017
Zheng Hewen, Singh Nischal, Shetye Gauri S, Jin Yucheng, Li Diana, Luk Yan-Yeung
Abstract excerpt
Rhamnolipids secreted by Pseudomonas aeruginosa are required for the bacteria to form biofilm efficiently and form biofilm with internal structures including pores and channels. In this work, we explore the effect of a class of synthetic analogs of rhamnolipids at controlling (promoting and inhibiting) the biofilm formation activities of a non-rhamnolipid-producing strain - rhlA - of P. aeruginosa. This class of...
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