Commentary: What is the case for candidate gene approaches in the era of high-throughput genomics? A response to Border and Keller (2017).

Abstract excerpt

Border and Keller argue that candidate gene approaches are outdated and out-of-touch with the current understanding of the genetic architecture of complex behavioral traits and should be abandoned in favor of unbiased, genome-wide approaches. Border and Keller further suggest that a candidate gene should not be selected for in-depth investigation unless identified by a well-powered genome-wide association study...

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