Article
Dynamics of the human gut microbiome in inflammatory bowel disease.
Nature microbiology - 13 Feb 2017
Halfvarson Jonas, Brislawn Colin J, Lamendella Regina, Vázquez-Baeza Yoshiki, Walters William A, Bramer Lisa M, D'Amato Mauro, Bonfiglio Ferdinando, McDonald Daniel, Gonzalez Antonio, McClure Erin E, Dunklebarger Mitchell F, Knight Rob, Jansson Janet K
Abstract excerpt
Inflammatory bowel disease (IBD) is characterized by flares of inflammation with a periodic need for increased medication and sometimes even surgery. The aetiology of IBD is partly attributed to a deregulated immune response to gut microbiome dysbiosis. Cross-sectional studies have revealed microbial signatures for different IBD subtypes, including ulcerative colitis, colonic Crohn's disease and ileal Crohn's...
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