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Article

Impact of the Secretome of Human Mesenchymal Stem Cells on Brain Structure and Animal Behavior in a Rat Model of Parkinson's Disease.

Stem cells translational medicine - 1 Feb 2017

Teixeira Fábio G, Carvalho Miguel M, Panchalingam Krishna M, Rodrigues Ana J, Mendes-Pinheiro Bárbara, Anjo Sandra, Manadas Bruno, Behie Leo A, Sousa Nuno, Salgado António J

Abstract excerpt

Research in the last decade strongly suggests that mesenchymal stem cell (MSC)-mediated therapeutic benefits are mainly due to their secretome, which has been proposed as a possible therapeutic tool for the treatment of Parkinson's disease (PD). Indeed, it has been shown that the MSC secretome increases neurogenesis and cell survival, and has numerous neuroprotective actions under different conditions....

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Source

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Identifiers

PMID: 28191785
DOI: 10.5966/sctm.2016-0071
PMCID: PMC5442797

Genes

MSC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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