Article
Virulence and immunogenicity of genetically defined human and porcine isolates of M. avium subsp. hominissuis in an experimental mouse infection.
PloS one - 1 Jan 2017
Bruffaerts Nicolas, Vluggen Christelle, Roupie Virginie, Duytschaever Lucille, Van den Poel Christophe, Denoël Joseph, Wattiez Ruddy, Letesson Jean-Jacques, Fretin David, Rigouts Leen, Chapeira Ophélie, Mathys Vanessa, Saegerman Claude, Huygen Kris
Abstract excerpt
Mycobacterium avium subsp. hominissuis (Mah) represents a health concern for humans and to a lesser extent for pigs, but its zoonotic potential remains elusive. Using multispacer sequence typing (MST) we previously identified 49 different genotypes of Mah among Belgian clinical and porcine isolates, with 5 MSTs shared by both hosts. Using experimental intranasal infection of BALB/c mice, we compared the virulence...
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