SLC12A3 variants modulate LDL cholesterol levels in the Mongolian population.

doi:10.1186/s12944-017-0413-x

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Article

SLC12A3 variants modulate LDL cholesterol levels in the Mongolian population.

Lipids in health and disease - 6 Feb 2017

An Caiyan, Zhang Kejin, Su Xiulan

Abstract excerpt

BACKGROUND: Abnormalities in lipid metabolism are crucial factors in the pathogenesis of cardiovascular disease (CVD). Variants of many genes have been verified to confer risk for lipid metabolism abnormalities. However, the relationship between genetic variants of the NCC-encoding SLC12A3 gene and lipid metabolism in the Mongolian population remains unclear. In the present study, we aimed to elucidate the...

Topics

Adult
Aged
Asian People
China
Cholesterol, LDL
Female
Gene Frequency
Genetic Association Studies
Haplotypes
Humans
Male
Middle Aged
Polymorphism, Single Nucleotide
Solute Carrier Family 12, Member 3
Young Adult

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Identifiers

PMID: 28166833
DOI: 10.1186/s12944-017-0413-x
PMCID: PMC5294767

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