Article
Association of MP6d9 Polymorphism with Clinical Variability in Cystic Fibrosis Patients.
Clinical laboratory - 1 Nov 2016
Sahli Chaima, Hadj-Fredj Sondess, Dabboubi Rym, Bousseta Khedija, Mehrzi Ahmed, Messaoud Taieb
Abstract excerpt
BACKGROUND: In this work, we are interested to study for the first time the extragenic polymorphic marker MP6d9 in cystic fibrosis and healthy cohort in Tunisia to establish the contribution of MP6d9 polymorphism in the phenotypic variability of CF patients. METHODS: Our study enrolled 112 CF patients and 100 healthy controls. The analysis of the polymorphic marker MP6d9 was performed using the PCR-RFLP...
Topics
- Adolescent
- Amplified Fragment Length Polymorphism Analysis
- Case-Control Studies
- Child
- Child, Preschool
- Cystic Fibrosis
- Cystic Fibrosis Transmembrane Conductance Regulator
- Female
- Gene Frequency
- Genetic Association Studies
- Genetic Markers
- Genetic Predisposition to Disease
- Humans