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Article

Contribution of FGFR1 Variants to Craniofacial Variations in East Asians.

PloS one - 1 Jan 2017

Adel Mohamed, Yamaguchi Tetsutaro, Tomita Daisuke, Nakawaki Takatoshi, Kim Yong-Il, Hikita Yu, Haga Shugo, Takahashi Masahiro, Nadim Mohamed A, Kawaguchi Akira, Isa Mutsumi, El-Kenany Walid H, El-Kadi Abbadi A, Park Soo-Byung, Ishida Hajime, Maki Koutaro, Kimura Ryosuke

Abstract excerpt

FGFR1 plays an important role in the development of the nervous system as well as the regulation of the skeletal development and bone homeostasis. Mutations in FGFR1 genes affect skull development, specifically suture and synchondrosis, resulting in craniosynostosis and facial abnormalities. We examined subjects with normal skull morphology for genetic polymorphisms that might be associated with normal...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Receptor, Fibroblast Growth Factor, Type 1

Source

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Identifiers

PMID: 28129408
DOI: 10.1371/journal.pone.0170645
PMCID: PMC5271310

Genes

FGFR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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