Article
Potential unfavorable impacts of BDNF Val66Met polymorphisms on metabolic risks in average population in a longevous area.
BMC geriatrics - 5 Jan 2017
Peng Jun-Hua, Liu Cheng-Wu, Pan Shang-Ling, Wu Hua-Yu, Liang Qing-Hua, Gan Rui-Jing, Huang Ling, Ding Yi, Bian Zhang-Ya, Huang Hao, Lv Ze-Ping, Zhou Xiao-Ling, Yin Rui-Xing
Abstract excerpt
BACKGROUND: Brain-derived neurotrophic factor (BDNF) has been implicated in cognitive performance and the modulation of several metabolic parameters in some disease models, but its potential roles in successful aging remain unclear. We herein sought to define the putative correlation between BDNF Val66Met and several metabolic risk factors including BMI, blood pressure, fasting plasma glucose (FPG) and lipid...
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