Article
Identification and characterization a novel HLA-A allele, A*02:355, by sequence-based typing in a Chinese potential donor.
International journal of immunogenetics - 1 Feb 2017
Nie X-M, Zhang Y, Qiao W-B, Zhu C-F, Zhao Y-R
Abstract excerpt
The new allele A*02:355 differs from A* 02:03:01 at positions 98 (T→A) and 102(A→C) resulting in an amino acid exchange F9→T. Interallelic sequence exchange is more likely the mechanism of its origination. The amino acid replacement influences the HLA peptide binding cleft and might have significant functional effects.
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