Article
Prevalence and severity of arterial calcifications in pseudoxanthoma elasticum (PXE) compared to hospital controls. Novel insights into the vascular phenotype of PXE.
Atherosclerosis - 1 Jan 2017
Kranenburg Guido, de Jong Pim A, Mali Willem P, Attrach Mohamed, Visseren Frank L J, Spiering Wilko
Abstract excerpt
BACKGROUND AND AIMS: Pseudoxanthoma elasticum (PXE) is a monogenetic disorder with progressive calcifications of the skin, the Bruch's membrane in the eyes and the arterial wall. Vascular disease is considered to be very prevalent, but the whole-body distribution of arterial calcifications in PXE is unknown. We aimed to systematically investigate arterial calcifications in PXE. METHODS: We included 104 PXE...
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