The paternal polymorphism rs5370 in the EDN1 gene decreases the risk of preeclampsia.

doi:10.1016/j.preghy.2016.07.002

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Article

The paternal polymorphism rs5370 in the EDN1 gene decreases the risk of preeclampsia.

Pregnancy hypertension - 1 Oct 2016

Galaviz-Hernandez Carlos, Arámbula-Meraz Eliakym, Medina-Bastidas Diana, Sosa-Macías Martha, Lazalde-Ramos Blanca P, Ortega-Chávez Margarita, Hernandez-García Lorena

Abstract excerpt

OBJECTIVE: To evaluate whether the maternal, paternal or the combined maternal/paternal contribution of SNP rs5370 of the EDN1 gene is associated with preeclampsia and drove its expression in placenta. STUDY DESIGN: This case-control study included 61 preeclamptic patients and their partners and 49 healthy pregnant women and their partners. The population was sub-divided into three groups: women-only, men-only...

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Identifiers

PMID: 27939477
DOI: 10.1016/j.preghy.2016.07.002

Genes

EDN1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

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