Article
Niemann-Pick disease, type C and Roscoe Brady.
Molecular genetics and metabolism - 1 Jan 2000
Patterson Marc C, Walkley Steven U
Abstract excerpt
The Niemann-Pick family of diseases was poorly understood until Roscoe Brady and his colleagues began their investigations in the 1960s. Following Brady's discovery of the defect in acid sphingomyelinase in Niemann-Pick disease, types A and B, Peter Pentchev, a senior scientist in the group, launched a series of investigations of an unusual lipid storage disease in a spontaneous mouse model. These led initially...
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