Article
Identification of laryngeal cancer prognostic biomarkers using an inflammatory gene-related, competitive endogenous RNA network.
Oncotarget - 7 Feb 2017
He Qun, Tian Linli, Jiang Hao, Zhang Jiarui, Li Qiang, Sun Yanan, Zhao Jiannan, Li Huijun, Liu Ming
Abstract excerpt
Competitive endogenous RNAs (ceRNAs) act as molecular sponges for microRNAs (miRNAs), and are associated with tumorigenesis in various cancers, including laryngeal cancer (LC). In this work, we constructed an LC-specific inflammatory gene-related ceRNA network (IceNet). In IceNet, ceRNAs targeting inflammation-related genes tended to be network hubs. Additionally, the betweenness centralities of these hub ceRNAs...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
