Article
Genomic signatures of Mannheimia haemolytica that associate with the lungs of cattle with respiratory disease, an integrative conjugative element, and antibiotic resistance genes.
BMC genomics - 29 Nov 2016
Clawson Michael L, Murray Robert W, Sweeney Michael T, Apley Michael D, DeDonder Keith D, Capik Sarah F, Larson Robert L, Lubbers Brian V, White Brad J, Kalbfleisch Theodore S, Schuller Gennie, Dickey Aaron M, Harhay Gregory P, Heaton Michael P, Chitko-McKown Carol G, Brichta-Harhay Dayna M, Bono James L, Smith Timothy P L
Abstract excerpt
BACKGROUND: Mannheimia haemolytica typically resides in cattle as a commensal member of the upper respiratory tract microbiome. However, some strains can invade their lungs and cause respiratory disease and death, including those with multi-drug resistance. A nucleotide polymorphism typing system was developed for M. haemolytica from the genome sequences of 1133 North American isolates, and used to identify...
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