Article
Identification of SP110 in horse (Equus caballus): Isolation of novel splice variants and evidence of activation effects on macrophages.
Tuberculosis (Edinburgh, Scotland) - 1 Dec 2016
Chen Qi, Tong Qi, Ge Hengtao, Li Wenzhong, Liu Jun, Wang Yongsheng, Guo Zekun, Quan Fusheng, Zhang Yong
Abstract excerpt
SP110 has previously shown to be a genetic determinant of host resistance to the intracellular pathogen infection in mouse and human. However, its relevant biological information in large non-primate animals still remains unknown. Here we report the novel discovery and characterization of three transcript variants of horse SP110. The transcript variant 1 (Tv1) of horse SP110 with the longest open reading frame...
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