Article
Adaptation of Escherichia coli traversing from the faecal environment to the urinary tract.
International journal of medical microbiology : IJMM - 1 Dec 2016
Nielsen Karen L, Stegger Marc, Godfrey Paul A, Feldgarden Michael, Andersen Paal S, Frimodt-Møller Niels
Abstract excerpt
The majority of extraintestinal pathogenic Escherichia coli (ExPEC) causing urinary tract infections (UTI) are found in the patient's own gut flora, but only limited knowledge is available on the potential adaptation that may occur in the bacteria in order to traverse the perineum and successfully infect the urinary tract. Here, matching pairs of faecal and UTI isolates from 42 patients were compared pairwise...
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