Article
Differential Infection Patterns and Recent Evolutionary Origins of Equine Hepaciviruses in Donkeys.
Journal of virology - 1 Jan 2017
Walter Stephanie, Rasche Andrea, Moreira-Soto Andrés, Pfaender Stephanie, Bletsa Magda, Corman Victor Max, Aguilar-Setien Alvaro, García-Lacy Fernando, Hans Aymeric, Todt Daniel, Schuler Gerhard, Shnaiderman-Torban Anat, Steinman Amir, Roncoroni Cristina, Veneziano Vincenzo, Rusenova Nikolina, Sandev Nikolay, Rusenov Anton, Zapryanova Dimitrinka, García-Bocanegra Ignacio, Jores Joerg, Carluccio Augusto, Veronesi Maria Cristina, Cavalleri Jessika M V, Drosten Christian, Lemey Philippe, Steinmann Eike, Drexler Jan Felix
Abstract excerpt
The hepatitis C virus (HCV) is a major human pathogen. Genetically related viruses in animals suggest a zoonotic origin of HCV. The closest relative of HCV is found in horses (termed equine hepacivirus [EqHV]). However, low EqHV genetic diversity implies relatively recent acquisition of EqHV by horses, making a derivation of HCV from EqHV unlikely. To unravel the EqHV evolutionary history within equid sister...
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