Article
Checkpoint Inhibitors in Metastatic EGFR-Mutated Non-Small Cell Lung Cancer-A Meta-Analysis.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer - 1 Feb 2017
Lee Chee Khoon, Man Johnathan, Lord Sally, Links Matthew, Gebski Val, Mok Tony, Yang James Chih-Hsin
Abstract excerpt
INTRODUCTION: We performed a meta-analysis to assess the role of immune checkpoint inhibitors as second-line therapy in EGFR-mutant advanced NSCLC. METHODS: Randomized trials comparing immune checkpoint inhibitors against chemotherapy were identified. We retrieved the hazard ratio (HR) and 95% confidence interval (CI) for overall survival (OS) of the intention-to-treat population and EGFR mutation-defined...
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