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Article

The Phylogeographic and Spatiotemporal Spread of HCV in Pakistani Population.

PloS one - 1 Jan 2016

Ghori Noor-Ul-Huda, Shafique Atif, Hayat Muhammad Qasim, Anjum Sadia

Abstract excerpt

Hepatitis C Virus (HCV) is the most prevalent human pathogen in Pakistan and is the major cause of liver cirrhosis and hepatocellular carcinoma in infected patients. It has shifted from being hypo-endemic to being hyper-endemic. There was no information about the origin and evolution of the local variants. Here we use newly developed phyloinformatic methods of sequence analysis to conduct the first comprehensive...

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Identifiers

PMID: 27764129
DOI: 10.1371/journal.pone.0164265
PMCID: PMC5072696

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