Article
Immunophenotypic and prognostic analysis of PAX8 and TTF-1 expressions in neuroendocrine carcinomas of thymic origin: A comparative study with their pulmonary counterparts.
Journal of surgical oncology - 1 Nov 2016
Bi Yalan, Deng Yinghui, Li Shanqing, Zhou Xiaoyun, Chen Yeye, Ma Dongjie, Mao Xinxin, Guan Yuzhou, Chen Jie, Meng Yunxiao
Abstract excerpt
OBJECTIVES: To investigate the immunoreactivity of TTF-1 and PAX8 in neuroendocrine carcinoma of thymic (TNEC) and pulmonary origins (PNEC), and whether their immunophenotyping could be used to distinguish between NEC of the two sites, as well as prognosis of patients with TNEC. METHODS: Twenty-two cases of TNEC and 20 cases of PNEC were selected for immunohistochemical analysis using PAX8 and TTF-1. Clinical...
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