Article
Coexistence of obesity and asthma determines a distinct respiratory metabolic phenotype.
The Journal of allergy and clinical immunology - 1 May 2017
Maniscalco Mauro, Paris Debora, Melck Dominique J, D'Amato Maria, Zedda Anna, Sofia Matteo, Stellato Cristiana, Motta Andrea
Abstract excerpt
BACKGROUND: Epidemiologic and clinical evidence supports the existence of an obesity-related asthma phenotype. No distinct pathophysiologic elements or specific biomarkers have been identified thus far, but increased oxidative stress has been reported. OBJECTIVE: We aimed at verifying whether metabolomics of exhaled breath condensate from obese asthmatic (OA) patients, lean asthmatic (LA) patients, and obese...
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