Article
Up-regulation of ribosome biogenesis by MIR196A2 genetic variation promotes endometriosis development and progression.
Oncotarget - 22 Nov 2016
Chang Cherry Yin-Yi, Lai Ming-Tsung, Chen Yi, Yang Ching-Wen, Chang Hui-Wen, Lu Cheng-Chan, Chen Chih-Mei, Chan Carmen, Chung Ching, Tseng Chun-Cheng, Hwang Tritium, Sheu Jim Jinn-Chyuan, Tsai Fuu-Jen
Abstract excerpt
Aberrant miRNA expression has been reported in endometriosis and miRNA gene polymorphisms have been linked to cancer. Because certain ovarian cancers arise from endometriosis, we genotyped seven cancer-related miRNA single nucleotide polymorphisms (MiRSNPs) to investigate their possible roles in endometriosis. Genetic variants in MIR196A2 (rs11614913) and MIR100 (rs1834306) were found to be associated with...
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