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Celecoxib exhibits an anti-gastric cancer effect by targeting focal adhesion and leukocyte transendothelial migration-associated genes

8 Aug 2016

Abstract excerpt

Gastric cancer (GC) is a prevalent cancer, which remains incurable, and therefore requires an alternative treatment method. Celecoxib is a nonsteroidal anti‑inflammatory drug that targets cyclooxygenase‑2, and exhibits anticancer effects. The present study aimed to investigate the anti‑GC mechanism of celecoxib using bioinformatics methods. Gene expression datasets GSE56807 (GC tissues and normal gastric tissues)...

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PMID: 27698798
DOI: 10.3892/ol.2016.4976

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